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Pharmacologic Treatment of Acromegaly:

Introduction
Diagnosis
Goals of Therapy
Pharmacologic Therapy
Conclusion

Conclusion


Critical to improving the significant morbidity and mortality associated with acromegaly is early detection and appropriate treatment aimed at normalizing IGF-1 and GH levels, decreasing the signs and symptoms of the disease, and shrinking the tumor. Transsphenoidal surgery currently remains the first choice of treatment for patients with small, well-circumscribed tumors, with a strong role indicated for adjuvant medical therapy, especially after resection of larger tumors. Less commonly, radiation therapy is used for patients with residual disease and disease that is not responsive to medical treatment. Primary medical therapy with somatostatin analogs has emerged as an effective and safe treatment option for patients in whom surgery is not desired or is contraindicated.

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